Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors.

Cheng, Shi-Bin; Nakashima, Akitoshi; Huber, Warren J; Davis, Sarah; Banerjee, Sayani; Huang, Zheping; Saito, Shigeru; Sadovsky, Yoel; Sharma, Surendra

Cheng, Shi-Bin; Nakashima, Akitoshi; Huber, Warren J; Davis, Sarah; Banerjee, Sayani; Huang, Zheping; Saito, Shigeru; Sadovsky, Yoel; Sharma, Surendra.

Afiliação

Cheng SB; Departments of Pediatrics, Obstetrics and Gynecology and Pathology, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI, USA. scheng@wihri.org.
Nakashima A; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, Japan.
Huber WJ; Departments of Pediatrics, Obstetrics and Gynecology and Pathology, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Davis S; Departments of Pediatrics, Obstetrics and Gynecology and Pathology, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Banerjee S; Departments of Pediatrics, Obstetrics and Gynecology and Pathology, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Huang Z; Departments of Pediatrics, Obstetrics and Gynecology and Pathology, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Saito S; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, Japan.
Sadovsky Y; Magee-Womens Research Institute, Department of Obstetrics and Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
Sharma S; Departments of Pediatrics, Obstetrics and Gynecology and Pathology, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI, USA. ssharma@wihri.org.

Cell Death Dis ; 10(12): 927, 2019 12 05.

Article em En | MEDLINE | ID: mdl-31804457

Assuntos

Proteínas de Transporte/genética; Inflamação/genética; Proteína 3 que Contém Domínio de Pirina da Família NLR/genética; Pré-Eclâmpsia/genética; Adulto; Hipóxia Celular/genética; Estresse do Retículo Endoplasmático/genética; Feminino; Humanos; Inflamação/metabolismo; Inflamação/patologia; Peptídeos e Proteínas de Sinalização Intracelular/genética; Proteínas de Ligação a Fosfato/genética; Placenta/metabolismo; Placenta/patologia; Pré-Eclâmpsia/metabolismo; Pré-Eclâmpsia/patologia; Gravidez; Piroptose/genética; Transdução de Sinais; Trofoblastos/metabolismo; Trofoblastos/patologia; Resposta a Proteínas não Dobradas/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / Proteínas de Transporte / Proteína 3 que Contém Domínio de Pirina da Família NLR / Inflamação Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Cell Death Dis Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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