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Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria.
Surivet, Jean-Philippe; Panchaud, Philippe; Specklin, Jean-Luc; Diethelm, Stefan; Blumstein, Anne-Catherine; Gauvin, Jean-Christophe; Jacob, Loïc; Masse, Florence; Mathieu, Gaëlle; Mirre, Azely; Schmitt, Christine; Lange, Roland; Tidten-Luksch, Naomi; Gnerre, Carmela; Seeland, Swen; Herrmann, Charlyse; Seiler, Peter; Enderlin-Paput, Michel; Mac Sweeney, Aengus; Wicki, Micha; Hubschwerlen, Christian; Ritz, Daniel; Rueedi, Georg.
Afiliação
  • Surivet JP; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Panchaud P; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Specklin JL; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Diethelm S; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Blumstein AC; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Gauvin JC; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Jacob L; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Masse F; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Mathieu G; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Mirre A; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Schmitt C; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Lange R; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Tidten-Luksch N; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Gnerre C; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Seeland S; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Herrmann C; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Seiler P; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Enderlin-Paput M; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Mac Sweeney A; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Wicki M; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Hubschwerlen C; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Ritz D; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Rueedi G; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
J Med Chem ; 63(1): 66-87, 2020 01 09.
Article em En | MEDLINE | ID: mdl-31804826
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Infecções por Escherichia coli / Amidoidrolases / Bactérias Gram-Negativas / Ácidos Hidroxâmicos / Antibacterianos Limite: Animals Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Infecções por Escherichia coli / Amidoidrolases / Bactérias Gram-Negativas / Ácidos Hidroxâmicos / Antibacterianos Limite: Animals Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça