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A Novel Small Molecule Inhibits Intrahepatocellular Accumulation of Z-Variant Alpha 1-Antitrypsin In Vitro and In Vivo.
Zhang, Xiaojuan; Pham, Kien; Li, Danmeng; Schutte, Ryan J; Gonzalo, David Hernandez; Zhang, Penghui; Oshins, Regina; Tan, Weihong; Brantly, Mark; Liu, Chen; Ostrov, David A.
Afiliação
  • Zhang X; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32611, USA.
  • Pham K; Department of Pathology and Laboratory Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ 07103, USA.
  • Li D; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32611, USA.
  • Schutte RJ; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32611, USA.
  • Gonzalo DH; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32611, USA.
  • Zhang P; Center for Research at Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, UF Health Cancer Center, UF Genetics Institute and McKnight Brain Institute, University of Florida, Gainesville, FL 32611, USA.
  • Oshins R; The Key Laboratory of Biomedical Information Engineering of the Ministry of Education, School of Life Science and Technology, Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University, Xi'an 710049, China.
  • Tan W; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA.
  • Brantly M; Center for Research at Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, UF Health Cancer Center, UF Genetics Institute and McKnight Brain Institute, University of Florida, Gainesville, FL 32611, USA.
  • Liu C; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA.
  • Ostrov DA; Department of Pathology and Laboratory Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ 07103, USA.
Cells ; 8(12)2019 12 06.
Article em En | MEDLINE | ID: mdl-31817705

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Serina Proteinase / Alfa 1-Antitripsina / Hepatócitos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cells Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Serina Proteinase / Alfa 1-Antitripsina / Hepatócitos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cells Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Suíça