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HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells.
Arasu, Uma Thanigai; Deen, Ashik Jawahar; Pasonen-Seppänen, Sanna; Heikkinen, Sami; Lalowski, Maciej; Kärnä, Riikka; Härkönen, Kai; Mäkinen, Petri; Lázaro-Ibáñez, Elisa; Siljander, Pia R-M; Oikari, Sanna; Levonen, Anna-Liisa; Rilla, Kirsi.
Afiliação
  • Arasu UT; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland. uma.thanigai@uef.fi.
  • Deen AJ; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Pasonen-Seppänen S; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Heikkinen S; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Lalowski M; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
  • Kärnä R; Faculty of Medicine, Biochemistry and Developmental Biology, Meilahti Clinical Proteomics Core Facility, HiLIFE, University of Helsinki, Helsinki, Finland.
  • Härkönen K; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Mäkinen P; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Lázaro-Ibáñez E; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Siljander PR; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, Centre for Drug Research, University of Helsinki, Helsinki, Finland.
  • Oikari S; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, Centre for Drug Research, University of Helsinki, Helsinki, Finland.
  • Levonen AL; EV Group and EV Core, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
  • Rilla K; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Cell Mol Life Sci ; 77(20): 4093-4115, 2020 Oct.
Article em En | MEDLINE | ID: mdl-31820036
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Cima / Proteínas Proto-Oncogênicas c-myc / Proteínas Hedgehog / Vesículas Extracelulares / Hialuronan Sintases / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Mol Life Sci Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia País de publicação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Cima / Proteínas Proto-Oncogênicas c-myc / Proteínas Hedgehog / Vesículas Extracelulares / Hialuronan Sintases / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Mol Life Sci Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia País de publicação: Suíça