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Geniposidic acid ameliorates spatial learning and memory deficits and alleviates neuroinflammation via inhibiting HMGB-1 and downregulating TLR4/2 signaling pathway in APP/PS1 mice.
Zhou, Zhangjiuzhi; Hou, Jiawei; Mo, Yuyan; Ren, Mengqiao; Yang, Guang; Qu, Zuwei; Hu, Yanli.
Afiliação
  • Zhou Z; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, PR China; The First Affiliated Hospital of the Medical College, Shihezi University, XinJiang, 832000, PR China.
  • Hou J; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, PR China.
  • Mo Y; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, PR China.
  • Ren M; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, PR China.
  • Yang G; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, PR China.
  • Qu Z; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, PR China.
  • Hu Y; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, PR China. Electronic address: zwx330@163.com.
Eur J Pharmacol ; 869: 172857, 2020 Feb 15.
Article em En | MEDLINE | ID: mdl-31837991
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Glucosídeos Iridoides / Doença de Alzheimer / Transtornos da Memória / Anti-Inflamatórios Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2020 Tipo de documento: Article País de publicação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Glucosídeos Iridoides / Doença de Alzheimer / Transtornos da Memória / Anti-Inflamatórios Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2020 Tipo de documento: Article País de publicação: Holanda