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CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration.
Nobles, Christopher L; Sherrill-Mix, Scott; Everett, John K; Reddy, Shantan; Fraietta, Joseph A; Porter, David L; Frey, Noelle; Gill, Saar I; Grupp, Stephan A; Maude, Shannon L; Siegel, Donald L; Levine, Bruce L; June, Carl H; Lacey, Simon F; Melenhorst, J Joseph; Bushman, Frederic D.
Afiliação
  • Nobles CL; Department of Microbiology.
  • Sherrill-Mix S; Department of Microbiology.
  • Everett JK; Department of Microbiology.
  • Reddy S; Department of Microbiology.
  • Fraietta JA; Department of Microbiology.
  • Porter DL; Center for Cellular Immunotherapies.
  • Frey N; Department of Pathology and Laboratory Medicine, and.
  • Gill SI; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Grupp SA; Parker Institute for Cancer Immunotherapy, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Maude SL; Center for Cellular Immunotherapies.
  • Siegel DL; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Levine BL; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • June CH; Center for Cellular Immunotherapies.
  • Lacey SF; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Melenhorst JJ; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Bushman FD; Center for Cellular Immunotherapies.
J Clin Invest ; 130(2): 673-685, 2020 02 03.
Article em En | MEDLINE | ID: mdl-31845905

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Leucemia Linfocítica Crônica de Células B / Imunoterapia Adotiva / Antígenos CD19 / Vetores Genéticos Limite: Female / Humans / Male Idioma: En Revista: J Clin Invest Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Leucemia Linfocítica Crônica de Células B / Imunoterapia Adotiva / Antígenos CD19 / Vetores Genéticos Limite: Female / Humans / Male Idioma: En Revista: J Clin Invest Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos