Hydrophobically Modified let-7b miRNA Enhances Biodistribution to NSCLC and Downregulates HMGA2 In Vivo.

Segal, Meirav; Biscans, Annabelle; Gilles, Maud-Emmanuelle; Anastasiadou, Eleni; De Luca, Roberto; Lim, Jihoon; Khvorova, Anastasia; Slack, Frank J

Hydrophobically Modified let-7b miRNA Enhances Biodistribution to NSCLC and Downregulates HMGA2 In Vivo.

Segal, Meirav; Biscans, Annabelle; Gilles, Maud-Emmanuelle; Anastasiadou, Eleni; De Luca, Roberto; Lim, Jihoon; Khvorova, Anastasia; Slack, Frank J.

Afiliação

Segal M; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.
Biscans A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
Gilles ME; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.
Anastasiadou E; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.
De Luca R; HMS Initiative for RNA Medicine, Department of Neurology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.
Lim J; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.
Khvorova A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
Slack FJ; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA. Electronic address: fslack@bidmc.harvard.edu.

Mol Ther Nucleic Acids ; 19: 267-277, 2020 Mar 06.

Article em En | MEDLINE | ID: mdl-31855835

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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