Isolation and Characterization of a Heparin-Like Compound with Potent Anticoagulant and Fibrinolytic Activity from the Clam <i>Coelomactra antiquata</i>.

Du, ZhenXing; Jia, XueJing; Chen, Jing; Zhou, SiYi; Chen, JianPing; Liu, XiaoFei; Cao, XiaoHuang; Zhong, SaiYi; Hong, PengZhi

Isolation and Characterization of a Heparin-Like Compound with Potent Anticoagulant and Fibrinolytic Activity from the Clam Coelomactra antiquata.

Du, ZhenXing; Jia, XueJing; Chen, Jing; Zhou, SiYi; Chen, JianPing; Liu, XiaoFei; Cao, XiaoHuang; Zhong, SaiYi; Hong, PengZhi.

Afiliação

Du Z; School of Food Science and Technology, Guangdong Ocean University, Zhan Jiang 524088, China.
Jia X; Shenzhen institute, Guangdong Ocean University, Shen Zhen 518108, China.
Chen J; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Province Engineering Laboratory for Marine Biological Products, Zhan Jiang 524088, China.
Zhou S; School of Food Science and Technology, Guangdong Ocean University, Zhan Jiang 524088, China.
Chen J; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Province Engineering Laboratory for Marine Biological Products, Zhan Jiang 524088, China.
Liu X; School of Food Science and Technology, Guangdong Ocean University, Zhan Jiang 524088, China.
Cao X; Shenzhen institute, Guangdong Ocean University, Shen Zhen 518108, China.
Zhong S; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Province Engineering Laboratory for Marine Biological Products, Zhan Jiang 524088, China.
Hong P; School of Food Science and Technology, Guangdong Ocean University, Zhan Jiang 524088, China.

Mar Drugs ; 18(1)2019 Dec 19.

Article em En | MEDLINE | ID: mdl-31861572

Assuntos

Anticoagulantes/química; Anticoagulantes/isolamento & purificação; Fibrinolíticos/química; Fibrinolíticos/isolamento & purificação; Heparina/química; Heparina/isolamento & purificação; Animais; Anticoagulantes/farmacologia; Bivalves; Feminino; Fibrinolíticos/farmacologia; Heparina/análogos & derivados; Heparina/farmacologia; Humanos; Tempo de Tromboplastina Parcial; Tempo de Protrombina; Entorses e Distensões; Tempo de Trombina

Palavras-chave

anticoagulant activity; fibrinolytic activity; heparin; shellfish; structural characteristics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heparina / Fibrinolíticos / Anticoagulantes Limite: Animals / Female / Humans Idioma: En Revista: Mar Drugs Assunto da revista: BIOLOGIA / FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Suíça

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