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The efficacy of intradermal injections of botulinum toxin in the management of enlarged facial pores and seborrhea: a split face-controlled study.
Sayed, Khadiga S; Hegazy, Rehab; Gawdat, Heba I; Abdel Hay, Rania M; Ahmed, Mona M; Mohammed, Faisal Nouredin; Allam, Riham; Fahim, Aya.
Afiliação
  • Sayed KS; Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Hegazy R; Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Gawdat HI; Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Abdel Hay RM; Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Ahmed MM; Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Mohammed FN; Dermatology Department and Venereology, National Research Centre, Giza, Egypt.
  • Allam R; Ophthalmology Department, Faculty of Medicine, Cairo University, Giza, Egypt.
  • Fahim A; Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
J Dermatolog Treat ; 32(7): 771-777, 2021 Nov.
Article em En | MEDLINE | ID: mdl-31865815
BACKGROUND: Enlarged facial pores are becoming a matter of cosmetic concern. Injections of (botulinum toxin type A) have an increasing popularity among cosmetic procedures. OBJECTIVE: To determine the efficacy and safety of intradermal injection of botulinum toxin in treatment of excess sebum secretion and enlarged facial pores. MATERIALS AND METHODS: This split face-controlled pilot study was conducted on 20 patients with enlarged facial pores and seborrhea. One cheek was treated by intradermal injection of botulinum toxin, and the other was injected by saline. Patient assessment was performed after 1 and then after 4 months. RESULTS: At 1-month assessment, both sides showed significant reduction in their sebum and pore scores (p = .001), with significantly more improvement on the botulinum toxin-treated side. Dermoscopy documented a significant decrease in the average size of facial pores (p < .001), and the OCT demonstrated a significant increase in the dermal thickness (p < .001) with non-significant deference between both sides. Four months after treatment, the botulinum toxin-treated side maintained its improvement in both scores. CONCLUSION: Intradermal injection of botulinum toxin is an effective and safe procedure for the management of excess sebum and facial pores with acceptable results lasting for an average of 4 months.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dermatite Seborreica / Toxinas Botulínicas Tipo A / Fármacos Neuromusculares Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: J Dermatolog Treat Assunto da revista: DERMATOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Egito País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dermatite Seborreica / Toxinas Botulínicas Tipo A / Fármacos Neuromusculares Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: J Dermatolog Treat Assunto da revista: DERMATOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Egito País de publicação: Reino Unido