Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage.

Goulielmaki, Evi; Ioannidou, Anna; Tsekrekou, Maria; Stratigi, Kalliopi; Poutakidou, Ioanna K; Gkirtzimanaki, Katerina; Aivaliotis, Michalis; Evangelou, Konstantinos; Topalis, Pantelis; Altmüller, Janine; Gorgoulis, Vassilis G; Chatzinikolaou, Georgia; Garinis, George A

Goulielmaki, Evi; Ioannidou, Anna; Tsekrekou, Maria; Stratigi, Kalliopi; Poutakidou, Ioanna K; Gkirtzimanaki, Katerina; Aivaliotis, Michalis; Evangelou, Konstantinos; Topalis, Pantelis; Altmüller, Janine; Gorgoulis, Vassilis G; Chatzinikolaou, Georgia; Garinis, George A.

Afiliação

Goulielmaki E; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece.
Ioannidou A; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece.
Tsekrekou M; Department of Biology, University of Crete, Heraklion, Crete, Greece.
Stratigi K; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece.
Poutakidou IK; Department of Biology, University of Crete, Heraklion, Crete, Greece.
Gkirtzimanaki K; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece.
Aivaliotis M; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece.
Evangelou K; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece.
Topalis P; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece.
Altmüller J; Department of Histology and Embryology, Athens Medical School, GR11527, Athens, Greece.
Gorgoulis VG; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece.
Chatzinikolaou G; Cologne Center for Genomics (CCG), Institute for Genetics, University of Cologne, 50931, Cologne, Germany.
Garinis GA; Department of Histology and Embryology, Athens Medical School, GR11527, Athens, Greece.

Nat Commun ; 11(1): 42, 2020 01 02.

Article em En | MEDLINE | ID: mdl-31896748

Assuntos

Dano ao DNA/fisiologia; Exossomos/metabolismo; Macrófagos/citologia; Animais; Reparo do DNA; Proteínas de Ligação a DNA/genética; Proteínas de Ligação a DNA/metabolismo; Endonucleases/genética; Endonucleases/metabolismo; Exossomos/patologia; Regulação da Expressão Gênica; Glucose/metabolismo; Transportador de Glucose Tipo 1/metabolismo; Inflamação/genética; Inflamação/metabolismo; Inflamação/patologia; Macrófagos/metabolismo; Masculino; Camundongos Transgênicos; Neuropeptídeos/genética; Neuropeptídeos/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Proteínas rab de Ligação ao GTP/genética; Proteínas rab de Ligação ao GTP/metabolismo; Proteínas rac1 de Ligação ao GTP/genética; Proteínas rac1 de Ligação ao GTP/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Exossomos / Macrófagos Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Grécia País de publicação: Reino Unido

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