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Novel glucagon- and OXM-based peptides acting through glucagon and GLP-1 receptors with body weight reduction and anti-diabetic properties.
Cai, Xingguang; Li, Chengye; Zhou, Jie; Dai, Yuxuan; Avraham, Yosefa; Sun, Lidan; Liu, Chunxia; Tong, Jiayi; Wang, Yao; Bi, Xinzhou; He, Liang; Huang, Wenlong; Qian, Hai.
Afiliação
  • Cai X; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Li C; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Zhou J; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Dai Y; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Avraham Y; Department of Human Nutrition and Metabolism, Braun School of Public Health, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
  • Sun L; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Liu C; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Tong J; Zhongda Hospital, Southeast University, Nanjing 210009, PR China.
  • Wang Y; Zhongda Hospital, Southeast University, Nanjing 210009, PR China.
  • Bi X; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • He L; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Huang W; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China; Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Qian H; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China; Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China. Electronic addr
Bioorg Chem ; 95: 103538, 2020 01.
Article em En | MEDLINE | ID: mdl-31901754
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Glucagon / Redução de Peso / Diabetes Mellitus Experimental / Oxintomodulina / Receptor do Peptídeo Semelhante ao Glucagon 1 / Hipoglicemiantes Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Glucagon / Redução de Peso / Diabetes Mellitus Experimental / Oxintomodulina / Receptor do Peptídeo Semelhante ao Glucagon 1 / Hipoglicemiantes Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos