The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC.

Morrison, Gladys; Asiedu, Marina N; Priebe, Jessica M; Dunning, Jacqueline; Ghoreishi-Haack, Nayereh; Kroes, Roger A; Bowers, M Scott; Barth, Amanda L; Cearley, Cassia N; Moskal, Joseph R

Morrison, Gladys; Asiedu, Marina N; Priebe, Jessica M; Dunning, Jacqueline; Ghoreishi-Haack, Nayereh; Kroes, Roger A; Bowers, M Scott; Barth, Amanda L; Cearley, Cassia N; Moskal, Joseph R.

Afiliação

Morrison G; Aptinyx Inc., Evanston, IL, United States.
Asiedu MN; Aptinyx Inc., Evanston, IL, United States.
Priebe JM; Aptinyx Inc., Evanston, IL, United States.
Dunning J; Aptinyx Inc., Evanston, IL, United States.
Ghoreishi-Haack N; Aptinyx Inc., Evanston, IL, United States.
Kroes RA; Aptinyx Inc., Evanston, IL, United States.
Bowers MS; Falk Ctr. for Mol. Therapeutics, McCormick School of Engineering, Northwestern University, Evanston, IL, United States.
Barth AL; Aptinyx Inc., Evanston, IL, United States.
Cearley CN; Falk Ctr. for Mol. Therapeutics, McCormick School of Engineering, Northwestern University, Evanston, IL, United States.
Moskal JR; Aptinyx Inc., Evanston, IL, United States.

Neurobiol Pain ; 7: 100039, 2020.

Article em En | MEDLINE | ID: mdl-31909296

Palavras-chave

Chronic Constriction injury (CCI); Medial prefrontal cortex; NMDAR's; Neuropathic pain; Src kinase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Neurobiol Pain Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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