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Berberine mitigates high glucose-induced podocyte apoptosis by modulating autophagy via the mTOR/P70S6K/4EBP1 pathway.
Li, Chao; Guan, Xi-Mei; Wang, Rui-Yao; Xie, Yong-Sheng; Zhou, Hong; Ni, Wei-Jian; Tang, Li-Qin.
Afiliação
  • Li C; Department of Pharmacy, Anhui Provincial Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China.
  • Guan XM; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui 230012, China.
  • Wang RY; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui 230012, China.
  • Xie YS; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China.
  • Zhou H; Department of Pharmacy, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui 230001, China.
  • Ni WJ; Department of Pharmacy, Anhui Provincial Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China; Department of Pharmacy, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui 23000
  • Tang LQ; Department of Pharmacy, Anhui Provincial Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China. Electronic address: tangliqin@ustc.edu.cn.
Life Sci ; 243: 117277, 2020 Feb 15.
Article em En | MEDLINE | ID: mdl-31926252

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Berberina / Apoptose / Proteínas de Ciclo Celular / Proteínas Quinases S6 Ribossômicas 70-kDa / Proteínas Adaptadoras de Transdução de Sinal / Podócitos / Serina-Treonina Quinases TOR / Glucose Limite: Animals Idioma: En Revista: Life Sci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Berberina / Apoptose / Proteínas de Ciclo Celular / Proteínas Quinases S6 Ribossômicas 70-kDa / Proteínas Adaptadoras de Transdução de Sinal / Podócitos / Serina-Treonina Quinases TOR / Glucose Limite: Animals Idioma: En Revista: Life Sci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Holanda