Nicotine Suppresses the Invasiveness of Human Trophoblasts by Downregulation of CXCL12 Expression through the Alpha-7 Subunit of the Nicotinic Acetylcholine Receptor.

Chen, Jing; Qiu, Min; Huang, Zirui; Chen, Jimei; Zhou, Chengbin; Han, Fengzhen; Qu, Yanji; Wang, Sheng; Zhuang, Jian; Li, Xiaohong

Chen, Jing; Qiu, Min; Huang, Zirui; Chen, Jimei; Zhou, Chengbin; Han, Fengzhen; Qu, Yanji; Wang, Sheng; Zhuang, Jian; Li, Xiaohong.

Afiliação

Chen J; Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences,School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Qiu M; Research Department of Medical Science, Guangdong Provincial People's Hospital, Guangzhou, China.
Huang Z; Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences,School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Chen J; Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.
Zhou C; Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences,School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Han F; Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.
Qu Y; Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences,School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Wang S; Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.
Zhuang J; Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences,School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Li X; Department of Obstetrics and Gynecology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.

Reprod Sci ; 27(3): 916-924, 2020 03.

Article em En | MEDLINE | ID: mdl-31933163

Assuntos

Quimiocina CXCL12/metabolismo; Regulação para Baixo/efeitos dos fármacos; Nicotina/administração & dosagem; Trofoblastos/efeitos dos fármacos; Trofoblastos/metabolismo; Receptor Nicotínico de Acetilcolina alfa7/metabolismo; Linhagem Celular; Feminino; Humanos; Placentação/efeitos dos fármacos; Gravidez

Palavras-chave

CXCL12; Invasion; Nicotine; Trophoblast; nAChR

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trofoblastos / Regulação para Baixo / Quimiocina CXCL12 / Receptor Nicotínico de Acetilcolina alfa7 / Nicotina Limite: Female / Humans / Pregnancy Idioma: En Revista: Reprod Sci Assunto da revista: MEDICINA REPRODUTIVA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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