Scaffold Hopping-Driven Optimization of 4-(Quinazolin-4-yl)-3,4-dihydroquinoxalin-2(1<i>H</i>)-ones as Novel Tubulin Inhibitors.

Jiang, Li; Goto, Masuo; Zhu, Dong-Qing; Hsu, Pei-Ling; Li, Kang-Po; Cui, Mutian; He, Xiaoyang; Morris-Natschke, Susan Lynne; Lee, Kuo-Hsiung; Xie, Lan

Scaffold Hopping-Driven Optimization of 4-(Quinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-ones as Novel Tubulin Inhibitors.

Jiang, Li; Goto, Masuo; Zhu, Dong-Qing; Hsu, Pei-Ling; Li, Kang-Po; Cui, Mutian; He, Xiaoyang; Morris-Natschke, Susan Lynne; Lee, Kuo-Hsiung; Xie, Lan.

Afiliação

Jiang L; Beijing Institute of Pharmacology and Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
Goto M; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Zhu DQ; Beijing Institute of Pharmacology and Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
Hsu PL; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Li KP; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Cui M; Beijing Institute of Pharmacology and Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
He X; Beijing Institute of Radiation Medicine, 27 Tai-Ping Road, Beijing 100850, China.
Morris-Natschke SL; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Lee KH; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Xie L; Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung, Taiwan.

ACS Med Chem Lett ; 11(1): 83-89, 2020 Jan 09.

Article em En | MEDLINE | ID: mdl-31938468

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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