Design, Synthesis, and In Vitro Evaluation of Benzofuro[3,2-<i>c</i>]Quinoline Derivatives as Potential Antileukemia Agents.

Lin, Ying; Xing, Dong; Wu, Wen-Biao; Xu, Gao-Ya; Yu, Li-Fang; Tang, Jie; Zhou, Yu-Bo; Li, Jia; Yang, Fan

Design, Synthesis, and In Vitro Evaluation of Benzofuro[3,2-c]Quinoline Derivatives as Potential Antileukemia Agents.

Lin, Ying; Xing, Dong; Wu, Wen-Biao; Xu, Gao-Ya; Yu, Li-Fang; Tang, Jie; Zhou, Yu-Bo; Li, Jia; Yang, Fan.

Afiliação

Lin Y; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.
Xing D; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.
Wu WB; National Center for Drug Screening, Shanghai Institute of Material Medica, Chinese Academy of Science, Shanghai 201203, China.
Xu GY; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
Yu LF; National Center for Drug Screening, Shanghai Institute of Material Medica, Chinese Academy of Science, Shanghai 201203, China.
Tang J; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
Zhou YB; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.
Li J; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.
Yang F; Shanghai Greenchem & Biotech Co. Ltd., Shanghai 200062, China.

Molecules ; 25(1)2020 Jan 03.

Article em En | MEDLINE | ID: mdl-31947824

Assuntos

Antineoplásicos; Desenho de Fármacos; Leucemia; Quinolinas; Antineoplásicos/síntese química; Antineoplásicos/química; Antineoplásicos/farmacologia; Linhagem Celular Tumoral; Ensaios de Seleção de Medicamentos Antitumorais; Humanos; Leucemia/tratamento farmacológico; Leucemia/metabolismo; Leucemia/patologia; Quinolinas/síntese química; Quinolinas/química; Quinolinas/farmacologia

Palavras-chave

3-(2-methoxyphenyl)quinolin-4(1H)one; MV-4-11 cell line; antileukemia activity; benzofuro[3,2-c]quinolines

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Desenho de Fármacos / Leucemia / Antineoplásicos Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Suíça

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