Antivenom Neutralization of Coagulopathic Snake Venom Toxins Assessed by Bioactivity Profiling Using Nanofractionation Analytics.

Xie, Chunfang; Slagboom, Julien; Albulescu, Laura-Oana; Bruyneel, Ben; Still, Kristina B M; Vonk, Freek J; Somsen, Govert W; Casewell, Nicholas R; Kool, Jeroen

Xie, Chunfang; Slagboom, Julien; Albulescu, Laura-Oana; Bruyneel, Ben; Still, Kristina B M; Vonk, Freek J; Somsen, Govert W; Casewell, Nicholas R; Kool, Jeroen.

Afiliação

Xie C; Division of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Slagboom J; Centre for Analytical Sciences Amsterdam (CASA), 1098 XH Amsterdam, The Netherlands.
Albulescu LO; Division of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Bruyneel B; Centre for Analytical Sciences Amsterdam (CASA), 1098 XH Amsterdam, The Netherlands.
Still KBM; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Vonk FJ; Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.
Somsen GW; Division of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Casewell NR; Centre for Analytical Sciences Amsterdam (CASA), 1098 XH Amsterdam, The Netherlands.
Kool J; Division of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.

Toxins (Basel) ; 12(1)2020 01 16.

Article em En | MEDLINE | ID: mdl-31963329

Assuntos

Antivenenos; Proteômica; Venenos de Víboras; Animais; Coagulação Sanguínea; Bothrops; Cromatografia Líquida; Ensaios de Triagem em Larga Escala; Espectrometria de Massas; Metaloproteases; Peptídeos; Fosfolipases A2; Daboia; Serina Proteases; Mordeduras de Serpentes; Viperidae

Palavras-chave

anticoagulation; antivenom; coagulation; nanofractionation; snakebite

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Venenos de Víboras / Antivenenos / Proteômica Limite: Animals Idioma: En Revista: Toxins (Basel) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

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