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Oxymatrine suppresses IL-1ß-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Wei, Kang; Dai, Jun; Wang, Zhenggang; Pei, Yaping; Chen, Yan; Ding, Yifan; Ding, Qing; Ahati, Paerxiati; Zhou, Xiaozhong; Wang, Huan; Fang, Huang.
Afiliação
  • Wei K; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
  • Dai J; Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
  • Wang Z; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
  • Pei Y; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
  • Chen Y; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
  • Ding Y; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
  • Ding Q; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
  • Ahati P; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
  • Zhou X; Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
  • Wang H; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
  • Fang H; Department of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Exp Biol Med (Maywood) ; 245(6): 532-541, 2020 03.
Article em En | MEDLINE | ID: mdl-31979980
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolizinas / NF-kappa B / Apoptose / Alcaloides / Receptor 4 Toll-Like / Degeneração do Disco Intervertebral / Núcleo Pulposo Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Exp Biol Med (Maywood) Assunto da revista: BIOLOGIA / FISIOLOGIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolizinas / NF-kappa B / Apoptose / Alcaloides / Receptor 4 Toll-Like / Degeneração do Disco Intervertebral / Núcleo Pulposo Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Exp Biol Med (Maywood) Assunto da revista: BIOLOGIA / FISIOLOGIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido