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Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-ß Peptide Aggregation and Reduces the Toxicity of Its Oligomers.
Ghadami, Seyyed Abolghasem; Chia, Sean; Ruggeri, Francesco Simone; Meisl, Georg; Bemporad, Francesco; Habchi, Johnny; Cascella, Roberta; Dobson, Christopher M; Vendruscolo, Michele; Knowles, Tuomas P J; Chiti, Fabrizio.
Afiliação
  • Ghadami SA; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", Section of Biochemistry, University of Florence, 50134 Florence, Italy.
  • Chia S; Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Cambridge CB2 1EW, U.K.
  • Ruggeri FS; Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Cambridge CB2 1EW, U.K.
  • Meisl G; Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Cambridge CB2 1EW, U.K.
  • Bemporad F; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", Section of Biochemistry, University of Florence, 50134 Florence, Italy.
  • Habchi J; Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Cambridge CB2 1EW, U.K.
  • Cascella R; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", Section of Biochemistry, University of Florence, 50134 Florence, Italy.
  • Dobson CM; Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Cambridge CB2 1EW, U.K.
  • Vendruscolo M; Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Cambridge CB2 1EW, U.K.
  • Knowles TPJ; Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Cambridge CB2 1EW, U.K.
  • Chiti F; Department of Physics, Cavendish Laboratory, 19 J. J. Thomson Avenue, Cambridge CB3 0HE, U.K.
Biomacromolecules ; 21(3): 1112-1125, 2020 03 09.
Article em En | MEDLINE | ID: mdl-32011129
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Doença de Alzheimer Limite: Humans Idioma: En Revista: Biomacromolecules Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Doença de Alzheimer Limite: Humans Idioma: En Revista: Biomacromolecules Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália País de publicação: Estados Unidos