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Depression and dementia from hyponatremia in brain cancer patients exposed to frozen food chemicals.
Khalid, Sana; Shahid, Saman; Rasheed, Sajid; Iftikhar, Sadaf; Hussain, Syed Shahzad; Ghayyur, Aysha; Chaudhry, Muhammad Nawaz.
Afiliação
  • Khalid S; College of Earth & Environmental Sciences (CEES), University of the Punjab, Lahore Pakistan.
  • Shahid S; Department of Sciences & Humanities, National University of Computer & Emerging Sciences (NUCES), Foundation for Advancement of Science and Technology (FAST), Lahore Pakistan.
  • Rasheed S; College of Earth & Environmental Sciences (CEES), University of the Punjab, Lahore Pakistan.
  • Iftikhar S; Department of Neurology, King Edward Medical University, Mayo Hospital, Lahore Pakistan.
  • Hussain SS; Department of Neurosurgery, Allama Iqbal Medical College (AIMC), Jinnah Hospital, Lahore Pakistan.
  • Ghayyur A; Department of Medicine, Allama Iqbal Medical College (AIMC), Jinnah Hospital, Lahore Pakistan.
  • Chaudhry MN; Department of Environmental Sciences & Policy, Lahore School of Economics (LSE), Lahore Pakistan.
Pak J Pharm Sci ; 32(6(Supplementary)): 2859-2864, 2019 Nov.
Article em En | MEDLINE | ID: mdl-32024625
ABSTRACT
Frozen food chemicals contain neurotoxins which disturb electrolyte levels. Altered electrolyte levels can induce mental illnesses. This study was focused on finding the prevalence of depression, dementia, intake of antidepressants and electrolytic alterations in brain cancer (BC) patients and in control group (CG) who were taking frozen and canned food. The levels of electrolytes were compared in both groups through Mann-Whitney U test. The Odds Ratio (OR) and Relative Risks (RR) were calculated of having a specific occurrence or condition of brain cancer patients vs. controls. Majority (41.42%) patients were from the age group 33-57 years. There were 52% male and 47% female patients. There was more occurrence of dementia (41%) and depression (6%) in patients as compared to CG. 94% patients were found with dementia. 32% patients were having low levels of sodium and 43% were having low levels of potassium. High levels of potassium (26%) were found in CG. 76% patients and 73% controls were taking canned food in moderation. 69% patients and 50% controls were taking frozen food in moderation. The potassium levels (p value 0.00001) and sodium levels (p value 0.01468) were found at significant difference in brain cancer patients and control group. Statistically significantly higher odds of outcome (OR>1) and increased relative risks (RR) were reported in dementia, depression and intake of anti-depressants for BC vs. CG. This epidemiological study reports hyponatremia as a significantly different parameter between brain cancer patients and controls. Food's chemicals induce hyponatremia, which can disturb mental states to develop different neurological conditions.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Demência / Depressão / Alimentos Congelados / Hiponatremia Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Pak J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Demência / Depressão / Alimentos Congelados / Hiponatremia Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Pak J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article