Tumor Cell-associated Exosomes Robustly Elicit Anti-tumor Immune Responses through Modulating Dendritic Cell Vaccines in Lung Tumor.

Wang, Ce; Huang, Xue; Wu, Yingjuan; Wang, Jingbo; Li, Furong; Guo, Guoqing

Wang, Ce; Huang, Xue; Wu, Yingjuan; Wang, Jingbo; Li, Furong; Guo, Guoqing.

Afiliação

Wang C; Department of anatomy, School of Medicine, Jinan University, Guangzhou 510632, China.
Huang X; Shenzhen Key Laboratory of Stem cell research and clinical transformation, Guangdong Engineering Technology Research Center of Stem cell and Cell therapy, Translational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenz
Wu Y; Shenzhen Key Laboratory of Stem cell research and clinical transformation, Guangdong Engineering Technology Research Center of Stem cell and Cell therapy, Translational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenz
Wang J; Shenzhen Key Laboratory of Stem cell research and clinical transformation, Guangdong Engineering Technology Research Center of Stem cell and Cell therapy, Translational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenz
Li F; Shenzhen Key Laboratory of Stem cell research and clinical transformation, Guangdong Engineering Technology Research Center of Stem cell and Cell therapy, Translational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenz
Guo G; Shenzhen Key Laboratory of Stem cell research and clinical transformation, Guangdong Engineering Technology Research Center of Stem cell and Cell therapy, Translational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenz

Int J Biol Sci ; 16(4): 633-643, 2020.

Article em En | MEDLINE | ID: mdl-32025211

Assuntos

Vacinas Anticâncer/imunologia; Vacinas Anticâncer/uso terapêutico; Células Dendríticas/metabolismo; Exossomos/metabolismo; Neoplasias Pulmonares/imunologia; Neoplasias Pulmonares/metabolismo; Células A549; Animais; Western Blotting; Linfócitos T CD8-Positivos/metabolismo; Feminino; Humanos; Marcação In Situ das Extremidades Cortadas; Neoplasias Pulmonares/prevenção & controle; Camundongos; Camundongos Endogâmicos C57BL; Linfócitos T Reguladores/metabolismo

Palavras-chave

DC vaccine; immune response; immunosuppression; lung tumor; tumor cell-associated exosome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Vacinas Anticâncer / Exossomos / Neoplasias Pulmonares Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Int J Biol Sci Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Austrália

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