A traditional Chinese Medicine, YXQN, Reduces Amyloid-induced Cytotoxicity by Inhibiting Aß42 Aggregation and Fibril Formation.

Wang, Lichun; Liu, Sitong; Xu, Jiaqi; Watanabe, Nobumoto; Di, Jun; Wei, Wei; Mayo, Kevin H; Li, Jiang; Li, Xiaomeng

Wang, Lichun; Liu, Sitong; Xu, Jiaqi; Watanabe, Nobumoto; Di, Jun; Wei, Wei; Mayo, Kevin H; Li, Jiang; Li, Xiaomeng.

Afiliação

Wang L; The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Liu S; The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Xu J; School of Life Sciences, Jilin University, Changchun 130012, China.
Watanabe N; The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Di J; Bioprobe Application Research Unit, RIKEN Center for Sustainable Resource Science, Wako, Saitama 351-0198, Japan.
Wei W; Jilin Province People's Hospital, Chanchun 130021, China.
Mayo KH; The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Li J; Dental Hospital, Jilin University, Changchun 130021, China.
Li X; Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN 55455, United States.

Curr Pharm Des ; 26(7): 780-789, 2020.

Article em En | MEDLINE | ID: mdl-32031066

Assuntos

Doença de Alzheimer; Peptídeos beta-Amiloides; Medicamentos de Ervas Chinesas/uso terapêutico; Fragmentos de Peptídeos; Agregação Patológica de Proteínas/tratamento farmacológico; Idoso; Doença de Alzheimer/tratamento farmacológico; Amiloide; Humanos; Medicina Tradicional Chinesa

Palavras-chave

Alzheimer's disease; Aß-induced cytotoxicity; Aß42 aggregation; YXQN; aggregation; fibrogenesis.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Medicamentos de Ervas Chinesas / Peptídeos beta-Amiloides / Doença de Alzheimer / Agregação Patológica de Proteínas Tipo de estudo: Diagnostic_studies Limite: Aged / Humans Idioma: En Revista: Curr Pharm Des Assunto da revista: FARMACIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Emirados Árabes Unidos

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