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Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration.
Cipriani, Valentina; Lorés-Motta, Laura; He, Fan; Fathalla, Dina; Tilakaratna, Viranga; McHarg, Selina; Bayatti, Nadhim; Acar, Ilhan E; Hoyng, Carel B; Fauser, Sascha; Moore, Anthony T; Yates, John R W; de Jong, Eiko K; Morgan, B Paul; den Hollander, Anneke I; Bishop, Paul N; Clark, Simon J.
Afiliação
  • Cipriani V; William Harvey Research Institute, Clinical Pharmacology, Queen Mary University of London, London, EC1M 6BQ, UK. v.cipriani@qmul.ac.uk.
  • Lorés-Motta L; UCL Institute of Ophthalmology, University College London, London, EC1V 9EL, UK. v.cipriani@qmul.ac.uk.
  • He F; Moorfields Eye Hospital NHS Foundation Trust, London, EC1V 2PD, UK. v.cipriani@qmul.ac.uk.
  • Fathalla D; UCL Genetics Institute, University College London, London, WC1E 6BT, UK. v.cipriani@qmul.ac.uk.
  • Tilakaratna V; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, 6525 GA, The Netherlands.
  • McHarg S; Division of Evolution and Genomic Sciences, Faculty of Biology Medicine and Health, School of Biological Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
  • Bayatti N; Systems Immunity URI, Division of Infection and Immunity, and UK DRI Cardiff, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
  • Acar IE; Division of Evolution and Genomic Sciences, Faculty of Biology Medicine and Health, School of Biological Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
  • Hoyng CB; Division of Evolution and Genomic Sciences, Faculty of Biology Medicine and Health, School of Biological Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
  • Fauser S; Division of Evolution and Genomic Sciences, Faculty of Biology Medicine and Health, School of Biological Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
  • Moore AT; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, 6525 GA, The Netherlands.
  • Yates JRW; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, 6525 GA, The Netherlands.
  • de Jong EK; Department of Ophthalmology, University Hospital of Cologne, Cologne, 50924, Germany.
  • Morgan BP; Roche Pharma Research and Early Development, F. Hoffmann-La Roche Ltd, Basel, 4070, Switzerland.
  • den Hollander AI; UCL Institute of Ophthalmology, University College London, London, EC1V 9EL, UK.
  • Bishop PN; Moorfields Eye Hospital NHS Foundation Trust, London, EC1V 2PD, UK.
  • Clark SJ; Ophthalmology Department, University of California San Francisco, San Francisco, CA, USA.
Nat Commun ; 11(1): 778, 2020 02 07.
Article em En | MEDLINE | ID: mdl-32034129
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteínas / Polimorfismo de Nucleotídeo Único / Degeneração Macular Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteínas / Polimorfismo de Nucleotídeo Único / Degeneração Macular Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido