Beta-arrestins operate an on/off control switch for focal adhesion kinase activity.

Alexander, Revu Ann; Lot, Isaure; Saha, Kusumika; Abadie, Guillaume; Lambert, Mireille; Decosta, Eleonore; Kobayashi, Hiroyuki; Beautrait, Alexandre; Borrull, Aurélie; Asnacios, Atef; Bouvier, Michel; Scott, Mark G H; Marullo, Stefano; Enslen, Hervé

Alexander, Revu Ann; Lot, Isaure; Saha, Kusumika; Abadie, Guillaume; Lambert, Mireille; Decosta, Eleonore; Kobayashi, Hiroyuki; Beautrait, Alexandre; Borrull, Aurélie; Asnacios, Atef; Bouvier, Michel; Scott, Mark G H; Marullo, Stefano; Enslen, Hervé.

Afiliação

Alexander RA; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Lot I; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Saha K; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Abadie G; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Lambert M; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Decosta E; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Kobayashi H; Department of Biochemistry and the Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, H3C 3J7, Canada.
Beautrait A; Department of Biochemistry and the Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, H3C 3J7, Canada.
Borrull A; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Asnacios A; Laboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Université de Paris, Paris, France.
Bouvier M; Department of Biochemistry and the Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, H3C 3J7, Canada.
Scott MGH; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Marullo S; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Enslen H; Institut Cochin, Inserm U 1016, CNRS UMR8104, Université de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France. herve.enslen@inserm.fr.

Cell Mol Life Sci ; 77(24): 5259-5279, 2020 Dec.

Article em En | MEDLINE | ID: mdl-32040695

Assuntos

Proteína-Tirosina Quinases de Adesão Focal/genética; Complexos Multiproteicos/genética; Neoplasias/genética; beta-Arrestinas/genética; Complexo 2 de Proteínas Adaptadoras/genética; Animais; Membrana Celular/genética; Proteína-Tirosina Quinases de Adesão Focal/metabolismo; Proteínas de Ligação ao GTP/genética; Células HEK293; Humanos; Camundongos; Complexos Multiproteicos/metabolismo; Neoplasias/tratamento farmacológico; Fosforilação/efeitos dos fármacos; Ligação Proteica/genética; Domínios Proteicos/genética; Receptor Tipo 1 de Angiotensina/genética; Receptores Acoplados a Proteínas G/genética; Vasopressinas/farmacologia

Palavras-chave

AP-2; Beta-arrestin; FAK; G proteins; G-protein-coupled receptors; ß-Arrestin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complexos Multiproteicos / Proteína-Tirosina Quinases de Adesão Focal / Beta-Arrestinas / Neoplasias Limite: Animals / Humans Idioma: En Revista: Cell Mol Life Sci Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: França País de publicação: Suíça

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