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A nanobody targeting the LIN28:let-7 interaction fragment of TUT4 blocks uridylation of let-7.
Yu, Chunxiao; Wang, Longfei; Rowe, R Grant; Han, Areum; Ji, Wanying; McMahon, Conor; Baier, Alexander S; Huang, Yu-Chung; Marion, William; Pearson, Daniel S; Kruse, Andrew C; Daley, George Q; Wu, Hao; Sliz, Piotr.
Afiliação
  • Yu C; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
  • Wang L; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
  • Rowe RG; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
  • Han A; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115.
  • Ji W; Division of Hematology/Oncology, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115.
  • McMahon C; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115.
  • Baier AS; Division of Hematology/Oncology, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115.
  • Huang YC; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
  • Marion W; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
  • Pearson DS; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
  • Kruse AC; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115.
  • Daley GQ; Division of Hematology/Oncology, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115.
  • Wu H; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115.
  • Sliz P; Division of Hematology/Oncology, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115.
Proc Natl Acad Sci U S A ; 117(9): 4653-4663, 2020 03 03.
Article em En | MEDLINE | ID: mdl-32060122
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Terminações 3' de RNA / MicroRNAs / Proteínas de Ligação a DNA / Anticorpos de Domínio Único Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Terminações 3' de RNA / MicroRNAs / Proteínas de Ligação a DNA / Anticorpos de Domínio Único Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos