A dysfunctional family environment and a high body fat percentage negatively affect telomere length in Mexican boys aged 8-10 years.
Acta Paediatr
; 109(10): 2091-2098, 2020 10.
Article
em En
| MEDLINE
| ID: mdl-32064679
ABSTRACT
AIM:
The aim of this study was to determine whether a direct relationship existed between absolute telomere length (aTL), obesity and familial functionality in a group of Mexican children.METHODS:
We recruited 134 children (52% boys) aged 8-10 years during regular primary care check-ups in 2016 and evaluated physical activity (PA), feeding practices, anthropometrics, body fat percentage (BF%) and family dysfunction. Optimised quantitative PCR determined aTL from genomic deoxyribonucleic acid isolated from saliva samples.RESULTS:
Boys with a healthy BF% showed a higher aTL than their high BF% counterparts (P < .01). aTL was higher in children who performed PA than their sedentary counterparts (P < .05). Alarmingly, 90% of the children belonged to dysfunctional families and a dysfunctional family was correlated with a higher BF% (r = -.57). Negative correlations between the BF% and aTL (r = -.1765) and the BF% and time dedicated to PA (r = -.031) were observed in boys. On the contrary, we found a positive correlation between the aTL and weekly PA (r = .1938). These correlations were not observed in girls.CONCLUSION:
Telomere shortening was associated with a high BF% in boys, but not girls. Dysfunctional families were also a key factor. School PA programmes should be mandatory.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tecido Adiposo
/
Telômero
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Child
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Female
/
Humans
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Male
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Acta Paediatr
Ano de publicação:
2020
Tipo de documento:
Article
País de publicação:
NO
/
NORUEGA
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NORWAY