Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons.

Mavrovic, Martina; Uvarov, Pavel; Delpire, Eric; Vutskits, Laszlo; Kaila, Kai; Puskarjov, Martin

Mavrovic, Martina; Uvarov, Pavel; Delpire, Eric; Vutskits, Laszlo; Kaila, Kai; Puskarjov, Martin.

Afiliação

Mavrovic M; Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Uvarov P; Neuroscience Center, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
Delpire E; Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Vutskits L; Neuroscience Center, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
Kaila K; Department of Anesthesiology, Vanderbilt University, Nashville, TN, USA.
Puskarjov M; Department of Basic Neurosciences, University of Geneva Medical School, Geneva 4, Switzerland.

EMBO Rep ; 21(4): e48880, 2020 04 03.

Article em En | MEDLINE | ID: mdl-32064760

Assuntos

Apoptose; Epilepsia; Neurônios/patologia; Simportadores/genética; Apoptose/genética; Cloretos/metabolismo; Humanos; Neurônios/metabolismo

Palavras-chave

GABA; KCC2; cell death; chloride; cofilin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Simportadores / Epilepsia / Neurônios Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: EMBO Rep Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia País de publicação: Reino Unido

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