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CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts.
Slowikowski, Kamil; Nguyen, Hung N; Noss, Erika H; Simmons, Daimon P; Mizoguchi, Fumitaka; Watts, Gerald F M; Gurish, Michael F; Brenner, Michael B; Raychaudhuri, Soumya.
Afiliação
  • Slowikowski K; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Nguyen HN; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Noss EH; Broad Institute of MIT and Harvard, Cambridge, MA 02142.
  • Simmons DP; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115.
  • Mizoguchi F; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA 02115.
  • Watts GFM; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Gurish MF; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Brenner MB; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Raychaudhuri S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
Proc Natl Acad Sci U S A ; 117(10): 5532-5541, 2020 03 10.
Article em En | MEDLINE | ID: mdl-32079724

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Proteínas Repressoras / Fatores de Transcrição / Fator de Necrose Tumoral alfa / Proteínas de Homeodomínio / Interleucina-17 / Proteínas Adaptadoras de Transdução de Sinal / Transcriptoma / Fibroblastos / Inflamação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Proteínas Repressoras / Fatores de Transcrição / Fator de Necrose Tumoral alfa / Proteínas de Homeodomínio / Interleucina-17 / Proteínas Adaptadoras de Transdução de Sinal / Transcriptoma / Fibroblastos / Inflamação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos