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Skin of atopic dermatitis patients shows disturbed ß-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition.
Boer, Daphne E C; van Smeden, Jeroen; Al-Khakany, Hanin; Melnik, Elizaveta; van Dijk, Rianne; Absalah, Samira; Vreeken, Rob J; Haenen, Caroline C P; Lavrijsen, Adriana P M; Overkleeft, Herman S; Aerts, Johannes M F G; Bouwstra, Joke A.
Afiliação
  • Boer DEC; Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands.
  • van Smeden J; Leiden Academic Centre for Drug Research, Leiden, the Netherlands; Centre for Human Drug Research, Leiden, the Netherlands.
  • Al-Khakany H; Leiden Academic Centre for Drug Research, Leiden, the Netherlands.
  • Melnik E; Centre for Human Drug Research, Leiden, the Netherlands.
  • van Dijk R; Leiden Academic Centre for Drug Research, Leiden, the Netherlands.
  • Absalah S; Leiden Academic Centre for Drug Research, Leiden, the Netherlands.
  • Vreeken RJ; Leiden Academic Centre for Drug Research, Leiden, the Netherlands; M4I Institute, Maastricht University, Maastricht, the Netherlands.
  • Haenen CCP; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Lavrijsen APM; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Overkleeft HS; Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands.
  • Aerts JMFG; Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands.
  • Bouwstra JA; Leiden Academic Centre for Drug Research, Leiden, the Netherlands. Electronic address: bouwstra@lacdr.leidenuniv.nl.
Biochim Biophys Acta Mol Cell Biol Lipids ; 1865(6): 158673, 2020 06.
Article em En | MEDLINE | ID: mdl-32092464
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esfingomielina Fosfodiesterase / Dermatite Atópica / Epiderme / Metabolismo dos Lipídeos / Glucosilceramidase Tipo de estudo: Observational_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Biochim Biophys Acta Mol Cell Biol Lipids Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Holanda
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esfingomielina Fosfodiesterase / Dermatite Atópica / Epiderme / Metabolismo dos Lipídeos / Glucosilceramidase Tipo de estudo: Observational_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Biochim Biophys Acta Mol Cell Biol Lipids Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Holanda