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TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice.
Zhao, Mingming; Zhao, Lin; Xiong, Xuelian; He, Yuan; Huang, Wei; Liu, Zihao; Ji, Liang; Pan, Bing; Guo, Xuefeng; Wang, Leibo; Cheng, Si; Xu, Ming; Yang, Hongyuan; Yin, Yuxin; Garcia-Barrio, Minerva T; Chen, Y Eugene; Meng, Xiangbao; Zheng, Lemin.
Afiliação
  • Zhao M; The Institute of Cardiovascular Sciences and Institute of Systems Biomedicine, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Health Science Center, Peking
  • Zhao L; Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Xiong X; Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
  • He Y; National Research Institute for Health and Family Planning, Beijing, China.
  • Huang W; Gene Therapy Center and the Institute of Hypertension, Internal Medicine Department and Cardiovascular Division, Department of Internal Medicine, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology, Wuhan, China.
  • Liu Z; Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
  • Ji L; The Institute of Cardiovascular Sciences and Institute of Systems Biomedicine, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Health Science Center, Peking
  • Pan B; The Institute of Cardiovascular Sciences and Institute of Systems Biomedicine, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Health Science Center, Peking
  • Guo X; Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
  • Wang L; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Cheng S; China National Clinical Research Center for Neurological Diseases, Tiantan Hospital, Advanced Innovation Center for Human Brain Protection, The Capital Medical University, Beijing, China.
  • Xu M; Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing, China.
  • Yang H; School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, New South Wales, Australia.
  • Yin Y; The Institute of Systems Biomedicine, Peking University, Beijing, China.
  • Garcia-Barrio MT; Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan.
  • Chen YE; Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan.
  • Meng X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Zheng L; The Institute of Cardiovascular Sciences and Institute of Systems Biomedicine, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Health Science Center, Peking
Gastroenterology ; 158(8): 2266-2281.e27, 2020 06.
Article em En | MEDLINE | ID: mdl-32105727
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Valeratos / Gama-Butirobetaína Dioxigenase / Hepatopatia Gordurosa não Alcoólica / Microbioma Gastrointestinal / Intestinos / Fígado Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Aged80 Idioma: En Revista: Gastroenterology Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Valeratos / Gama-Butirobetaína Dioxigenase / Hepatopatia Gordurosa não Alcoólica / Microbioma Gastrointestinal / Intestinos / Fígado Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Aged80 Idioma: En Revista: Gastroenterology Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos