Inhibition of profibrotic signalling enhances the 5-azacytidine-induced reprogramming of fibroblasts into cardiomyocytes.

Jia, Yangyang; Chang, Yuqiao; Sun, Panwen; Li, He; Guo, Zhikun

Jia, Yangyang; Chang, Yuqiao; Sun, Panwen; Li, He; Guo, Zhikun.

Afiliação

Jia Y; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang Medical University, Xinxiang 453003, PR China.
Chang Y; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang Medical University, Xinxiang 453003, PR China.
Sun P; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang Medical University, Xinxiang 453003, PR China.
Li H; Department of Histology and Embryology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China. Electronic address: heli@mails.tjmu.edu.cn.
Guo Z; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang Medical University, Xinxiang 453003, PR China. Electronic address: guozhikunxxmc@126.com.

Int J Biochem Cell Biol ; 122: 105733, 2020 05.

Article em En | MEDLINE | ID: mdl-32114121

Assuntos

Azacitidina/uso terapêutico; Fibroblastos/efeitos dos fármacos; Miócitos Cardíacos/efeitos dos fármacos; Animais; Azacitidina/farmacologia; Humanos; Ratos; Transdução de Sinais

Palavras-chave

5-azacytidine; Cardiac fibroblasts; Differentiation; Induced cardiomyocytes; TGF-ß inhibitor

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azacitidina / Miócitos Cardíacos / Fibroblastos Limite: Animals / Humans Idioma: En Revista: Int J Biochem Cell Biol Assunto da revista: BIOQUIMICA Ano de publicação: 2020 Tipo de documento: Article País de publicação: Holanda

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google