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The bifunctional enzyme, GenB4, catalyzes the last step of gentamicin 3',4'-di-deoxygenation via reduction and transamination activities.
Chen, Xiaotang; Zhang, Hui; Zhou, Shaotong; Bi, Mingjun; Qi, Shizhou; Gao, Huiyuan; Ni, Xianpu; Xia, Huanzhang.
Afiliação
  • Chen X; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang, Liaoning, China.
  • Zhang H; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang, Liaoning, China.
  • Zhou S; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang, Liaoning, China.
  • Bi M; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang, Liaoning, China.
  • Qi S; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang, Liaoning, China.
  • Gao H; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang, Liaoning, China.
  • Ni X; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang, Liaoning, China. nixianpu126@126.com.
  • Xia H; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang, Liaoning, China. hzxia@syphu.edu.cn.
Microb Cell Fact ; 19(1): 62, 2020 Mar 10.
Article em En | MEDLINE | ID: mdl-32156271
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Proteínas de Bactérias / Gentamicinas / Micromonospora / Antibacterianos Idioma: En Revista: Microb Cell Fact Assunto da revista: BIOTECNOLOGIA / MICROBIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Proteínas de Bactérias / Gentamicinas / Micromonospora / Antibacterianos Idioma: En Revista: Microb Cell Fact Assunto da revista: BIOTECNOLOGIA / MICROBIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido