Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection.

Zou, Xin; Chen, Ke; Zou, Jiawei; Han, Peiyi; Hao, Jie; Han, Zeguang

Zou, Xin; Chen, Ke; Zou, Jiawei; Han, Peiyi; Hao, Jie; Han, Zeguang.

Afiliação

Zou X; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Centre for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
Chen K; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Centre for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zou J; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Centre for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
Han P; Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Hao J; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Centre for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China. j.hao@sjtu.edu.cn.
Han Z; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Centre for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China. hanzg@sjtu.edu.cn.

Front Med ; 14(2): 185-192, 2020 Apr.

Article em En | MEDLINE | ID: mdl-32170560

Assuntos

Betacoronavirus/fisiologia; Infecções por Coronavirus/genética; Peptidil Dipeptidase A/genética; Pneumonia Viral/genética; Enzima de Conversão de Angiotensina 2; COVID-19; Humanos; Especificidade de Órgãos; Pandemias; RNA-Seq; Fatores de Risco; SARS-CoV-2; Análise de Célula Única

Palavras-chave

2019-nCoV; ACE2; single-cell RNA-seq

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Peptidil Dipeptidase A / Betacoronavirus Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Front Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: China

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