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Novel conjugates of endoperoxide and 4-anilinoquinazoline induce myeloma cell apoptosis by inhibiting the IGF1-R/AKT/mTOR signaling pathway.
Xu, Yujia; Zeng, Kun; Wang, Xiaoge; Zhang, Jieyu; Cao, Biyin; Zhang, Zubin; Qiao, Chunhua; Xu, Xiaofeng; Wang, Qi; Zeng, Yuanying; Mao, Xinliang.
Afiliação
  • Xu Y; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Zeng K; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Wang X; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Zhang J; Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Cao B; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Zhang Z; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Qiao C; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Xu X; Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
  • Wang Q; Department of Urology, Nanjing Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China.
  • Zeng Y; Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Mao X; Department of Oncology, Suzhou Municipal Hospital, Suzhou, Jiangsu, China.
Biosci Trends ; 14(2): 96-103, 2020 May 21.
Article em En | MEDLINE | ID: mdl-32173687
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Inibidores de Proteínas Quinases / Mieloma Múltiplo / Antineoplásicos Limite: Humans Idioma: En Revista: Biosci Trends Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Japão
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Inibidores de Proteínas Quinases / Mieloma Múltiplo / Antineoplásicos Limite: Humans Idioma: En Revista: Biosci Trends Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Japão