Applicability of Supercritical fluid chromatography-Mass spectrometry to metabolomics. II-Assessment of a comprehensive library of metabolites and evaluation of biological matrices.

Losacco, Gioacchino Luca; Ismail, Omar; Pezzatti, Julian; González-Ruiz, Víctor; Boccard, Julien; Rudaz, Serge; Veuthey, Jean-Luc; Guillarme, Davy

Losacco, Gioacchino Luca; Ismail, Omar; Pezzatti, Julian; González-Ruiz, Víctor; Boccard, Julien; Rudaz, Serge; Veuthey, Jean-Luc; Guillarme, Davy.

Afiliação

Losacco GL; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
Ismail O; Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Ferrara, via L. Borsari 46, 44121, Ferrara, Italy.
Pezzatti J; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
González-Ruiz V; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
Boccard J; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
Rudaz S; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
Veuthey JL; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
Guillarme D; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel-Servet 1, 1211, Geneva 4, Switzerland. Electronic address: Davy.guillarme@unige.ch.

J Chromatogr A ; 1620: 461021, 2020 Jun 07.

Article em En | MEDLINE | ID: mdl-32178859

Assuntos

Cromatografia com Fluido Supercrítico/métodos; Metaboloma; Metabolômica; Espectrometria de Massas em Tandem/métodos; Adenosina/sangue; Adenosina/urina; Humanos; Interações Hidrofóbicas e Hidrofílicas; Xanturenatos/sangue

Palavras-chave

Matrix effect; Metabolomics; Retention time variability; Supercritical fluid chromatography; UHPSFC-HRMS

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatografia com Fluido Supercrítico / Espectrometria de Massas em Tandem / Metaboloma / Metabolômica Limite: Humans Idioma: En Revista: J Chromatogr A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça País de publicação: Holanda

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