Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Development.

Huang, Chaoli; Liu, Tingting; Wang, Qihui; Hou, Weikang; Zhou, Cuihua; Song, Zeyuan; Shi, Yun Stone; Gao, Xiang; Chen, Guiquan; Yin, Zhenyu; Hu, Yimin

Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Development.

Huang, Chaoli; Liu, Tingting; Wang, Qihui; Hou, Weikang; Zhou, Cuihua; Song, Zeyuan; Shi, Yun Stone; Gao, Xiang; Chen, Guiquan; Yin, Zhenyu; Hu, Yimin.

Afiliação

Huang C; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Liu T; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Wang Q; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Hou W; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Zhou C; Department of Anesthesiology, The Second Affiliated Changzhou People's Hospital of Nanjing Medical University, Changzhou 213000, China.
Song Z; Department of Anesthesiology, The Second Affiliated Changzhou People's Hospital of Nanjing Medical University, Changzhou 213000, China.
Shi YS; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Gao X; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Chen G; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Yin Z; Department of Geriatric, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China.
Hu Y; Department of Anesthesiology, The Second Affiliated Changzhou People's Hospital of Nanjing Medical University, Changzhou 213000, China.

Cereb Cortex ; 30(7): 4183-4196, 2020 06 01.

Article em En | MEDLINE | ID: mdl-32186707

Assuntos

Células Ependimogliais/citologia; Neocórtex/embriologia; Células-Tronco Neurais/citologia; Proteína Fosfatase 2/genética; Junções Aderentes/metabolismo; Animais; Caderinas/metabolismo; Movimento Celular; Proliferação de Células/genética; Células Ependimogliais/metabolismo; Camundongos; Camundongos Knockout; Células-Tronco Neurais/metabolismo; Proteína Fosfatase 2/metabolismo; Telencéfalo/citologia

Palavras-chave

cortical development; protein phosphatase 2A; radial glial progenitor; stem cell niche; ventricular zone

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neocórtex / Proteína Fosfatase 2 / Células-Tronco Neurais / Células Ependimogliais Limite: Animals Idioma: En Revista: Cereb Cortex Assunto da revista: CEREBRO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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