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E-Cigarette, or Vaping, Product Use Associated Lung Injury (EVALI) with Acute Respiratory Failure in Three Adolescent Patients: a Clinical Timeline, Treatment, and Product Analysis.
Billa, Ramya; Tigges, Cody; Vijayakumar, Niranjan; Radke, Joshua; Pedati, Caitlin; Weiner, Rebecca; McCabe, Daniel.
Afiliação
  • Billa R; Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA, USA.
  • Tigges C; Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA, USA.
  • Vijayakumar N; Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA, USA.
  • Radke J; Department of Emergency Medicine, University of Iowa, Iowa City, IA, USA.
  • Pedati C; Iowa Department of Public Health, Des Moines, IA, USA.
  • Weiner R; Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA, USA.
  • McCabe D; Department of Emergency Medicine, University of Iowa, Iowa City, IA, USA. daniel-j-mccabe@uiowa.edu.
J Med Toxicol ; 16(3): 248-254, 2020 07.
Article em En | MEDLINE | ID: mdl-32193828
INTRODUCTION: E-cigarette, or vaping, product use associated lung injury (EVALI) has become a recent concern among public health officials. Factors that contribute to the concern include an increasing number of cases over time, the severity of the illness, and an unknown understanding of the pathophysiology and etiology of the illness. CASE SERIES: We cared for three adolescent patients with acute respiratory failure secondary to EVALI. All three patients were treated with high-dose steroids in addition to antimicrobials, which resulted in clinical improvement and resolution of their respiratory failure. Pulmonary function testing was performed on these previously healthy patients both acutely and subacutely. Additionally, we report the results from the laboratory analysis of one vaping device fluid which revealed previously unpublished components within these products. DISCUSSION: EVALI is a recent public health concern without a known etiology which can cause life-threatening lung injury in patients without prior lung pathology. We hope these cases will highlight the importance of return precautions in adolescents with vague respiratory symptoms and provide a cautionary tale to providers while they counsel patients regarding the use of these products.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Insuficiência Respiratória / Lesão Pulmonar / Sistemas Eletrônicos de Liberação de Nicotina / Vaping / Vapor do Cigarro Eletrônico / Pulmão Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Adolescent / Humans / Male Idioma: En Revista: J Med Toxicol Assunto da revista: TOXICOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Insuficiência Respiratória / Lesão Pulmonar / Sistemas Eletrônicos de Liberação de Nicotina / Vaping / Vapor do Cigarro Eletrônico / Pulmão Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Adolescent / Humans / Male Idioma: En Revista: J Med Toxicol Assunto da revista: TOXICOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos