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Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction.
Bautista-Niño, Paula K; Portilla-Fernandez, Eliana; Rubio-Beltrán, Eloisa; van der Linden, Janette J; de Vries, René; van Veghel, Richard; de Boer, Martine; Durik, Matej; Ridwan, Yanto; Brandt, Renata; Essers, Jeroen; Menzies, Robert I; Thomas, Rachel; de Bruin, Alain; Duncker, Dirk J; van Beusekom, Heleen M M; Ghanbari, Mohsen; Hoeijmakers, Jan H J; Sedlacek, Radislav; Touyz, Rhian M; Montezano, Augusto C; van der Pluijm, Ingrid; Danser, A H Jan; Haanes, Kristian A; Roks, Anton J M.
Afiliação
  • Bautista-Niño PK; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Portilla-Fernandez E; Fundacion Cardiovascular de Colombia FCV, Dept. of Cardiology, Bucaramanga, Colombia.
  • Rubio-Beltrán E; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van der Linden JJ; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • de Vries R; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van Veghel R; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • de Boer M; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Durik M; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Ridwan Y; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Brandt R; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Essers J; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Menzies RI; Department of Pediatric and Adolescent Medicine, Mayo Clinic College of Medicine, Rochester, MN, U.S.A.
  • Thomas R; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • de Bruin A; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Duncker DJ; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van Beusekom HMM; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Ghanbari M; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Hoeijmakers JHJ; Department of Vascular Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Sedlacek R; Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, U.K.
  • Touyz RM; Dutch Molecular Pathology Centre, Faculty of Veterinary Medicine, Department of Pathobiology, Utrecht University, Utrecht, The Netherlands.
  • Montezano AC; Dutch Molecular Pathology Centre, Faculty of Veterinary Medicine, Department of Pathobiology, Utrecht University, Utrecht, The Netherlands.
  • van der Pluijm I; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Danser AHJ; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Haanes KA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Roks AJM; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Clin Sci (Lond) ; 134(7): 727-746, 2020 04 17.
Article em En | MEDLINE | ID: mdl-32202295

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Envelhecimento / Endotélio Vascular / Senescência Celular / Células Endoteliais / Proteínas de Ligação a DNA / Reparo do DNA / Endonucleases Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Envelhecimento / Endotélio Vascular / Senescência Celular / Células Endoteliais / Proteínas de Ligação a DNA / Reparo do DNA / Endonucleases Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido