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Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells.
Sarkar, Tapash Jay; Quarta, Marco; Mukherjee, Shravani; Colville, Alex; Paine, Patrick; Doan, Linda; Tran, Christopher M; Chu, Constance R; Horvath, Steve; Qi, Lei S; Bhutani, Nidhi; Rando, Thomas A; Sebastiano, Vittorio.
Afiliação
  • Sarkar TJ; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
  • Quarta M; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
  • Mukherjee S; Department of Applied Physics, Stanford University School of Humanities and Sciences, Stanford, CA, 94305, USA.
  • Colville A; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, 94305, USA. mquarta@stanford.edu.
  • Paine P; Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA, 94305, USA. mquarta@stanford.edu.
  • Doan L; Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, 94304, USA. mquarta@stanford.edu.
  • Tran CM; Molecular Medicine Research Institute, Sunnyvale, CA, 94085, USA. mquarta@stanford.edu.
  • Chu CR; Department of Orthopedic Surgery, Stanford University School of Medicine, Sanford, CA, 94305, USA.
  • Horvath S; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, 94305, USA.
  • Qi LS; Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA, 94305, USA.
  • Bhutani N; Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, 94304, USA.
  • Rando TA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305, USA.
  • Sebastiano V; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Nat Commun ; 11(1): 1545, 2020 03 24.
Article em En | MEDLINE | ID: mdl-32210226
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rejuvenescimento / RNA Mensageiro / Núcleo Celular / Senescência Celular / Reprogramação Celular Limite: Adolescent / Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rejuvenescimento / RNA Mensageiro / Núcleo Celular / Senescência Celular / Reprogramação Celular Limite: Adolescent / Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido