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A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvß6 integrin inhibitor.
Maher, Toby M; Simpson, Juliet K; Porter, Joanna C; Wilson, Frederick J; Chan, Robert; Eames, Rhena; Cui, Yi; Siederer, Sarah; Parry, Simon; Kenny, Julia; Slack, Robert J; Sahota, Jagdeep; Paul, Lyn; Saunders, Peter; Molyneaux, Philip L; Lukey, Pauline T; Rizzo, Gaia; Searle, Graham E; Marshall, Richard P; Saleem, Azeem; Kang'ombe, Arthur R; Fairman, David; Fahy, William A; Vahdati-Bolouri, Mitra.
Afiliação
  • Maher TM; Royal Brompton Hospital, London, UK.
  • Simpson JK; National Heart and Lung Institute, Imperial College London, London, UK.
  • Porter JC; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Wilson FJ; University College London Hospital, London, UK.
  • Chan R; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Eames R; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Cui Y; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Siederer S; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Parry S; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Kenny J; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Slack RJ; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Sahota J; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Paul L; University College London Hospital, London, UK.
  • Saunders P; Royal Brompton Hospital, London, UK.
  • Molyneaux PL; Royal Brompton Hospital, London, UK.
  • Lukey PT; National Heart and Lung Institute, Imperial College London, London, UK.
  • Rizzo G; Royal Brompton Hospital, London, UK.
  • Searle GE; National Heart and Lung Institute, Imperial College London, London, UK.
  • Marshall RP; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Saleem A; Invicro, A Konica Minolta Company, London, UK.
  • Kang'ombe AR; Invicro, A Konica Minolta Company, London, UK.
  • Fairman D; GlaxoSmithKline Research and Development, Stevenage, UK.
  • Fahy WA; Invicro, A Konica Minolta Company, London, UK.
  • Vahdati-Bolouri M; GlaxoSmithKline Research and Development, Stevenage, UK.
Respir Res ; 21(1): 75, 2020 Mar 26.
Article em En | MEDLINE | ID: mdl-32216814

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirrolidinas / Butiratos / Integrinas / Volume de Ventilação Pulmonar / Fibrose Pulmonar Idiopática / Naftiridinas Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Female / Humans / Male Idioma: En Revista: Respir Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirrolidinas / Butiratos / Integrinas / Volume de Ventilação Pulmonar / Fibrose Pulmonar Idiopática / Naftiridinas Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Female / Humans / Male Idioma: En Revista: Respir Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido