Glycosylation of FcÎ³ receptors influences their interaction with various IgG1 glycoforms.

Cambay, Florian; Forest-Nault, Catherine; Dumoulin, Lea; Seguin, Alexis; Henry, Olivier; Durocher, Yves; De Crescenzo, Gregory

Cambay, Florian; Forest-Nault, Catherine; Dumoulin, Lea; Seguin, Alexis; Henry, Olivier; Durocher, Yves; De Crescenzo, Gregory.

Afiliação

Cambay F; Department of Chemical Engineering, Polytechnique Montréal, Montreal, Canada; Human Health Therapeutics Research Centre, National Research Council of Canada, Montreal, Canada.
Forest-Nault C; Department of Chemical Engineering, Polytechnique Montréal, Montreal, Canada; Human Health Therapeutics Research Centre, National Research Council of Canada, Montreal, Canada.
Dumoulin L; Department of Chemical Engineering, Polytechnique Montréal, Montreal, Canada.
Seguin A; Department of Chemical Engineering, Polytechnique Montréal, Montreal, Canada.
Henry O; Department of Chemical Engineering, Polytechnique Montréal, Montreal, Canada.
Durocher Y; Human Health Therapeutics Research Centre, National Research Council of Canada, Montreal, Canada; Department of Biochemistry and Molecular Medicine, University of Montreal, Montreal, Canada. Electronic address: yves.durocher@nrc.gc.ca.
De Crescenzo G; Department of Chemical Engineering, Polytechnique Montréal, Montreal, Canada. Electronic address: gregory.decrescenzo@polymtl.ca.

Mol Immunol ; 121: 144-158, 2020 05.

Article em En | MEDLINE | ID: mdl-32222585

Assuntos

Imunoglobulina G/metabolismo; Receptores de IgG/metabolismo; Animais; Células CHO; Cricetulus; Glicosilação; Células HEK293; Humanos; Imunoglobulina G/imunologia; Manose/metabolismo; Mutagênese Sítio-Dirigida; Polissacarídeos/metabolismo; Engenharia de Proteínas; Isoformas de Proteínas/genética; Isoformas de Proteínas/imunologia; Isoformas de Proteínas/metabolismo; Receptores de IgG/genética; Receptores de IgG/imunologia

Palavras-chave

Fc-gamma receptor; IgG; N-linked glycosylation; Protein-protein interaction; SPR; Site-directed mutagenesis

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Receptores de IgG Limite: Animals / Humans Idioma: En Revista: Mol Immunol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá País de publicação: Reino Unido

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google