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Discovery of new LXRß agonists as glioblastoma inhibitors.
Chen, Hao; Chen, Ziyang; Zhang, Zizhen; Li, Yali; Zhang, Shushu; Jiang, Fuqiang; Wei, Junkang; Ding, Peng; Zhou, Huihao; Gu, Qiong; Xu, Jun.
Afiliação
  • Chen H; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Chen Z; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Zhang Z; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Li Y; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Zhang S; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Jiang F; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Wei J; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Ding P; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
  • Zhou H; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China. Electronic address: zhuihao@mail.sysu.edu.cn.
  • Gu Q; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China. Electronic address: guqiong@mail.sysu.edu.cn.
  • Xu J; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Research Center for Drug Discovery at School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China. Electronic address: junxu@biochemomes.com.
Eur J Med Chem ; 194: 112240, 2020 May 15.
Article em En | MEDLINE | ID: mdl-32248003
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Compostos de Espiro / Glioblastoma / Descoberta de Drogas / Receptores X do Fígado / Oxindóis / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Compostos de Espiro / Glioblastoma / Descoberta de Drogas / Receptores X do Fígado / Oxindóis / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: França