A Multi-Dimensional Analysis of a Novel Approach for Wireless Stimulation.
IEEE Trans Biomed Eng
; 67(12): 3307-3316, 2020 12.
Article
em En
| MEDLINE
| ID: mdl-32248088
ABSTRACT
The elimination of integrated batteries in biomedical implants holds great promise for improving health outcomes in patients with implantable devices. However, despite extensive research in wireless power transfer, achieving efficient power transfer and effective operational range have remained a hindering challenge within anatomical constraints. OBJECTIVE:
We hereby demonstrate an intravascular wireless and batteryless microscale stimulator, designed for (1) low power dissipation via intermittent transmission and (2) reduced fixation mechanical burden via deployment to the anterior cardiac vein (ACV, â¼3.8 mm in diameter).METHODS:
We introduced a unique coil design circumferentially confined to a 3 mm diameter hollow-cylinder that was driven by a novel transmitter-based control architecture with improved power efficiency.RESULTS:
We examined wireless capacity using heterogenous bovine tissue, demonstrating >5 V stimulation threshold with up to 20 mm transmitter-receiver displacement and 20° of misalignment. Feasibility for human use was validated using Finite Element Method (FEM) simulation of the cardiac cycle, guided by pacer phantom-integrated Magnetic Resonance Images (MRI).CONCLUSION:
This system design thus enabled sufficient wireless power transfer in the face of extensive stimulator miniaturization.SIGNIFICANCE:
Our successful feasibility studies demonstrated the capacity for minimally invasive deployment and low-risk fixation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fontes de Energia Elétrica
/
Tecnologia sem Fio
Limite:
Animals
/
Humans
Idioma:
En
Revista:
IEEE Trans Biomed Eng
Ano de publicação:
2020
Tipo de documento:
Article