Targeted and sustained Sox9 expression in mouse hypertrophic chondrocytes causes severe and spontaneous osteoarthritis by perturbing cartilage homeostasis.

Liang, Bojian; Mamidi, Murali K; Samsa, William E; Chen, Yuqing; Lee, Brendan; Zheng, Qiping; Zhou, Guang

Liang, Bojian; Mamidi, Murali K; Samsa, William E; Chen, Yuqing; Lee, Brendan; Zheng, Qiping; Zhou, Guang.

Afiliação

Liang B; Department of Orthopaedics, Case Western Reserve University Cleveland, OH, USA.
Mamidi MK; Department of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University 126 Xiantai Blvd, Changchun 130033, Jilin, P. R. China.
Samsa WE; Department of Orthopaedics, Case Western Reserve University Cleveland, OH, USA.
Chen Y; Case Comprehensive Cancer Center, Case Western Reserve University Cleveland, OH, USA.
Lee B; Department of Orthopaedics, Case Western Reserve University Cleveland, OH, USA.
Zheng Q; Case Comprehensive Cancer Center, Case Western Reserve University Cleveland, OH, USA.
Zhou G; Department of Molecular and Human Genetics, Baylor College of Medicine Houston, TX, USA.

Am J Transl Res ; 12(3): 1056-1069, 2020.

Article em En | MEDLINE | ID: mdl-32269734

Palavras-chave

Col10a1; Hypertrophic chondrocytes; Sox9; adipogenesis; osteoarthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies Idioma: En Revista: Am J Transl Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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