Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2.

Mortensen, Anja C L; Morin, Eric; Brown, Christopher J; Lane, David P; Nestor, Marika

Mortensen, Anja C L; Morin, Eric; Brown, Christopher J; Lane, David P; Nestor, Marika.

Afiliação

Mortensen ACL; Department of Immunology, Genetics, and Pathology, The Rudbeck Laboratory, Uppsala University, SE-751 85, Uppsala, Sweden. anja.mortensen@igp.uu.se.
Morin E; Department of Immunology, Genetics, and Pathology, The Rudbeck Laboratory, Uppsala University, SE-751 85, Uppsala, Sweden.
Brown CJ; p53Lab, A*STAR, 8A Biomedical Grove, #06-04/05 Neuros/Immunos, Singapore, 138648, Singapore.
Lane DP; p53Lab, A*STAR, 8A Biomedical Grove, #06-04/05 Neuros/Immunos, Singapore, 138648, Singapore.
Nestor M; Department of Microbiology, Tumor and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.

EJNMMI Res ; 10(1): 38, 2020 Apr 16.

Article em En | MEDLINE | ID: mdl-32300907

Palavras-chave

3D tumor models; PM2; Radiosensitization; TRNT; pErk1/2 induction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: EJNMMI Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suécia

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