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Novel Drug Candidates Improve Ganglioside Accumulation and Neural Dysfunction in GM1 Gangliosidosis Models with Autophagy Activation.
Kajihara, Ryutaro; Numakawa, Tadahiro; Odaka, Haruki; Yaginuma, Yuji; Fusaki, Noemi; Okumiya, Toshika; Furuya, Hirokazu; Inui, Seiji; Era, Takumi.
Afiliação
  • Kajihara R; Department of Cell Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan; Department of Biomedical Laboratory Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0976, Japan.
  • Numakawa T; Department of Cell Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan.
  • Odaka H; Department of Cell Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan.
  • Yaginuma Y; Department of Morphological and Physiological Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0976, Japan.
  • Fusaki N; University Research Administration Center, Office of Research Promotion, Tohoku University, Tohoku 980-8577, Japan.
  • Okumiya T; Department of Biomedical Laboratory Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0976, Japan.
  • Furuya H; Department of Neurology, Kochi Medical School, Kochi University, Kochi 783-8505, Japan.
  • Inui S; Department of Biomedical Laboratory Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0976, Japan.
  • Era T; Department of Cell Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan. Electronic address: tera@kumamoto-u.ac.jp.
Stem Cell Reports ; 14(5): 909-923, 2020 05 12.
Article em En | MEDLINE | ID: mdl-32302553
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Gangliosidose GM1 / Fármacos Neuroprotetores / Gangliosídeo G(M1) / Neurônios Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Gangliosidose GM1 / Fármacos Neuroprotetores / Gangliosídeo G(M1) / Neurônios Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos