Predicting the outcome of respiratory disease in wheezing infants using tidal flow-volume loop shape.
Allergol Immunopathol (Madr)
; 48(4): 355-359, 2020.
Article
em En
| MEDLINE
| ID: mdl-32312562
ABSTRACT
INTRODUCTION AND OBJECTIVES:
Wheezing (RW) infants with a positive asthma predictive index (API+) have a lower lung function as measured by forced expiratory techniques. Tidal flow-volume loops (TFVL) are easy to perform in infants, and sedation is not necessary. MATERIALS ANDMETHODS:
A total of 216 wheezing infants were successfully measured, and 183 of them were followed for over a year. TFVL loops were classified into one of three categories depending of their geometric shape (symmetric, convex, and concave). Respiratory rate (Rr), presence of API+, and the number of exacerbations during the following year were also recorded.RESULTS:
Children with concave loops had more exacerbations in the following year (ORâ¯=â¯6.8 [IC95% 3.33;13.91]). Infants APIâ¯+â¯were also significantly more related to concave loops (ORâ¯=â¯10.02 [IC 95% 4.53; 22.15]). Rr was higher in infants with concave loops (44+/-15.5 vs. 36.6 +/-12.6; pâ¯<â¯0.01).CONCLUSION:
Infants with a concave TFVL have a higher probability of experiencing exacerbations in the following year, and are at a higher risk of suffering asthma.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Testes de Função Respiratória
/
Asma
/
Sons Respiratórios
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
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Infant
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Male
Idioma:
En
Revista:
Allergol Immunopathol (Madr)
Ano de publicação:
2020
Tipo de documento:
Article