Identifying Transcription Error-Enriched Genomic Loci Using Nuclear Run-on Circular-Sequencing Coupled with Background Error Modeling.

Cheung, Peter Pak-Hang; Jiang, Biaobin; Booth, Gregory T; Chong, Tin Hang; Unarta, Ilona Christy; Wang, Yuqing; Suarez, Gianmarco D; Wang, Jiguang; Lis, John T; Huang, Xuhui

Cheung, Peter Pak-Hang; Jiang, Biaobin; Booth, Gregory T; Chong, Tin Hang; Unarta, Ilona Christy; Wang, Yuqing; Suarez, Gianmarco D; Wang, Jiguang; Lis, John T; Huang, Xuhui.

Afiliação

Cheung PP; The Hong Kong University of Science and Technology-Shenzhen Research Institute, Hi-Tech Park, Nanshan, Shenzhen 518057, China; Department of Chemistry, Centre of Systems Biology and Human Health, State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clea
Jiang B; Division of Life Science, Department of Chemical and Biological Engineering, Centre of Systems Biology and Human Health, State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong; The HKUST Jockey Club Institute for Advanced Study
Booth GT; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
Chong TH; The Hong Kong University of Science and Technology-Shenzhen Research Institute, Hi-Tech Park, Nanshan, Shenzhen 518057, China.
Unarta IC; Bioengineering Graduate Program, Department of Biological and Chemical Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong.
Wang Y; Bioengineering Graduate Program, Department of Biological and Chemical Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong.
Suarez GD; Bioengineering Graduate Program, Department of Biological and Chemical Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong.
Wang J; Division of Life Science, Department of Chemical and Biological Engineering, Centre of Systems Biology and Human Health, State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong. Electronic address: jgwang@ust.hk.
Lis JT; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA; The HKUST Jockey Club Institute for Advanced Study (IAS), The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong. Electronic address: jtl10@cornell.edu.
Huang X; The Hong Kong University of Science and Technology-Shenzhen Research Institute, Hi-Tech Park, Nanshan, Shenzhen 518057, China; Department of Chemistry, Centre of Systems Biology and Human Health, State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clea

J Mol Biol ; 432(13): 3933-3949, 2020 06 12.

Article em En | MEDLINE | ID: mdl-32325070

Assuntos

RNA Polimerase I/genética; RNA/genética; Transcrição Gênica; Transcriptoma/genética; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; RNA Polimerase I/química; Processamento Pós-Transcricional do RNA/genética; RNA Ribossômico/química; RNA Ribossômico/genética

Palavras-chave

RNA polymerase I; RNA sequencing; Ribosomal RNA; transcription fidelity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / RNA Polimerase I / RNA / Transcriptoma Limite: Humans Idioma: En Revista: J Mol Biol Ano de publicação: 2020 Tipo de documento: Article País de publicação: Holanda

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