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The analysis of acetaminophen (paracetamol) and seven metabolites in rat, pig and human plasma by U(H)PLC-MS.
Dargue, Rebecca; Grant, Isobelle; Nye, Leanne C; Nicholls, Andy; Dare, Theo; Stahl, Simone H; Plumb, Robert S; Lee, Karla; Jalan, Rajiv; Coen, Muireann; Wilson, Ian D.
Afiliação
  • Dargue R; Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Grant I; Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Nye LC; Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Nicholls A; GlaxoSmithKline R&D, Park Road, Ware, Hertfordshire SG12 0DP, UK.
  • Dare T; GlaxoSmithKline R&D, Park Road, Ware, Hertfordshire SG12 0DP, UK.
  • Stahl SH; ADME Sciences, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Unit 310 Cambridge Science Park, Milton Road, Cambridge CB4 0WG, UK.
  • Plumb RS; WatersCorporation, Milford, MA 01757, USA.
  • Lee K; Department of Clinical Science & Services, Royal Veterinary College, University of London, Hertfordshire AL9 7TA, UK.
  • Jalan R; UCL Institute for Liver & Digestive Health, Royal Free Hospital, London NW3 2PF, UK.
  • Coen M; Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, UK.
  • Wilson ID; Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, UK.
Bioanalysis ; 12(7): 485-500, 2020 Apr.
Article em En | MEDLINE | ID: mdl-32343149

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasma / Cromatografia Líquida de Alta Pressão / Espectrometria de Massas em Tandem / Acetaminofen Limite: Animals / Humans Idioma: En Revista: Bioanalysis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasma / Cromatografia Líquida de Alta Pressão / Espectrometria de Massas em Tandem / Acetaminofen Limite: Animals / Humans Idioma: En Revista: Bioanalysis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido