Characterization of Endoplasmic Reticulum (ER) in Human Pluripotent Stem Cells Revealed Increased Susceptibility to Cell Death upon ER Stress.

Ha, Tae Won; Jeong, Ji Hun; Shin, HyeonSeok; Kim, Hyun Kyu; Im, Jeong Suk; Song, Byung Hoo; Hanna, Jacob; Oh, Jae Sang; Woo, Dong-Hun; Han, Jaeseok; Lee, Man Ryul

Ha, Tae Won; Jeong, Ji Hun; Shin, HyeonSeok; Kim, Hyun Kyu; Im, Jeong Suk; Song, Byung Hoo; Hanna, Jacob; Oh, Jae Sang; Woo, Dong-Hun; Han, Jaeseok; Lee, Man Ryul.

Afiliação

Ha TW; Soonchunhyang Institute of Medi-bio Science (SIMS), Soon Chun Hyang University, Cheonan 31151, Korea.
Jeong JH; Soonchunhyang Institute of Medi-bio Science (SIMS), Soon Chun Hyang University, Cheonan 31151, Korea.
Shin H; Soonchunhyang Institute of Medi-bio Science (SIMS), Soon Chun Hyang University, Cheonan 31151, Korea.
Kim HK; Soonchunhyang Institute of Medi-bio Science (SIMS), Soon Chun Hyang University, Cheonan 31151, Korea.
Im JS; Soonchunhyang Institute of Medi-bio Science (SIMS), Soon Chun Hyang University, Cheonan 31151, Korea.
Song BH; Soonchunhyang Institute of Medi-bio Science (SIMS), Soon Chun Hyang University, Cheonan 31151, Korea.
Hanna J; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 761001, Israel.
Oh JS; Department of Neurosurgery, College of Medicine, Soonchunhyang University, Cheonan Hospital, Cheonan 31151, Korea.
Woo DH; Laboratory of Stem Cells, NEXEL Co., Ltd., 8th floor, 55 Magokdong-ro, Gangseo-gu, Seoul 07802, Korea.
Han J; Soonchunhyang Institute of Medi-bio Science (SIMS), Soon Chun Hyang University, Cheonan 31151, Korea.
Lee MR; Soonchunhyang Institute of Medi-bio Science (SIMS), Soon Chun Hyang University, Cheonan 31151, Korea.

Cells ; 9(5)2020 04 26.

Article em En | MEDLINE | ID: mdl-32357563

Assuntos

Estresse do Retículo Endoplasmático/fisiologia; Retículo Endoplasmático/metabolismo; Células-Tronco Pluripotentes/citologia; Apoptose/fisiologia; Proteínas Estimuladoras de Ligação a CCAAT/metabolismo; Morte Celular/fisiologia; Retículo Endoplasmático/fisiologia; Fibroblastos/metabolismo; Humanos; Células-Tronco Pluripotentes/metabolismo; Transdução de Sinais/fisiologia; Resposta a Proteínas não Dobradas/fisiologia

Palavras-chave

C/EBP homologous protein (CHOP); ER stress; binding immunoglobulin protein (BiP); endoplasmic reticulum (ER); human pluripotent stem cells; proteostasis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes / Retículo Endoplasmático / Estresse do Retículo Endoplasmático Limite: Humans Idioma: En Revista: Cells Ano de publicação: 2020 Tipo de documento: Article País de publicação: Suíça

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